A carregar...
Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum
Huntingtin is a large HEAT repeat protein first identified in humans, where a polyglutamine tract expansion near the amino terminus causes a gain-of-function mechanism that leads to selective neuronal loss in Huntington's disease (HD). Genetic evidence in humans and knock-in mouse models sugges...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084204/ https://ncbi.nlm.nih.gov/pubmed/21552328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002052 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|