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Serum factors in older individuals change cellular clock properties

Human aging is accompanied by dramatic changes in daily sleep–wake behavior: Activity shifts to an earlier phase, and the consolidation of sleep and wake is disturbed. Although this daily circadian rhythm is brain-controlled, its mechanism is encoded by cell-autonomous circadian clocks functioning i...

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Autors principals: Pagani, Lucia, Schmitt, Karen, Meier, Fides, Izakovic, Jan, Roemer, Konstanze, Viola, Antoine, Cajochen, Christian, Wirz-Justice, Anna, Brown, Steven A., Eckert, Anne
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084079/
https://ncbi.nlm.nih.gov/pubmed/21482780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008882108
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