Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade

The syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever disease in children. However, the pathogenesis is unknown. Using a systems biology approach we analyzed blood samples from PFAPA patients whose genetic testing excluded h...

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Autori principali: Stojanov, Silvia, Lapidus, Sivia, Chitkara, Puja, Feder, Henry, Salazar, Juan C., Fleisher, Thomas A., Brown, Margaret R., Edwards, Kathryn M., Ward, Michael M., Colbert, Robert A., Sun, Hong-Wei, Wood, Geryl M., Barham, Beverly K., Jones, Anne, Aksentijevich, Ivona, Goldbach-Mansky, Raphaela, Athreya, Balu, Barron, Karyl S., Kastner, Daniel L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084055/
https://ncbi.nlm.nih.gov/pubmed/21478439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103681108
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