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Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes

Amphibian oocytes can rapidly and efficiently reprogram the transcription of transplanted somatic nuclei. To explore the factors and mechanisms involved, we focused on nuclear actin, an especially abundant component of the oocyte's nucleus (the germinal vesicle). The existence and significance...

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Autors principals: Miyamoto, Kei, Pasque, Vincent, Jullien, Jerome, Gurdon, John B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084028/
https://ncbi.nlm.nih.gov/pubmed/21536734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.615211
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