Structure of a CENP-A–histone H4 heterodimer in complex with chaperone HJURP

In higher eukaryotes, the centromere is epigenetically specified by the histone H3 variant Centromere Protein-A (CENP-A). Deposition of CENP-A to the centromere requires histone chaperone HJURP (Holliday junction recognition protein). The crystal structure of an HJURP–CENP-A–histone H4 complex shows...

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Detalhes bibliográficos
Main Authors: Hu, Hao, Liu, Yang, Wang, Mingzhu, Fang, Junnan, Huang, Hongda, Yang, Na, Li, Yanbo, Wang, Jianyu, Yao, Xuebiao, Shi, Yunyu, Li, Guohong, Xu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084024/
https://ncbi.nlm.nih.gov/pubmed/21478274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2045111
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