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Isolation and optimization of camelid single-domain antibodies: Dirk Saerens’ work on nanobodies

It is well established that all camelids have unique antibodies circulating in their blood. Unlike antibodies from all other species, these special antibodies are devoid of light chains, and are composed of a heavy chain homodimer. These so-called heavy-chain antibodies (HCAbs) are expressed after a...

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Detalhes bibliográficos
Autor principal: Saerens, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083966/
https://ncbi.nlm.nih.gov/pubmed/21537479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v1.i7.235
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