Pralatrexate in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results From the Pivotal PROPEL Study

PURPOSE: Peripheral T-cell lymphoma (PTCL) is a poor prognosis subtype of non-Hodgkin's lymphoma with no accepted standard of care. This study evaluated the efficacy and tolerability of pralatrexate, a novel antifolate with promising activity. PATIENTS AND METHODS: Patients with independently c...

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Main Authors: O'Connor, Owen A., Pro, Barbara, Pinter-Brown, Lauren, Bartlett, Nancy, Popplewell, Leslie, Coiffier, Bertrand, Jo Lechowicz, Mary, Savage, Kerry J., Shustov, Andrei R., Gisselbrecht, Christian, Jacobsen, Eric, Zinzani, Pier Luigi, Furman, Richard, Goy, Andre, Haioun, Corinne, Crump, Michael, Zain, Jasmine M., Hsi, Eric, Boyd, Adam, Horwitz, Steven
Format: Artigo
Language:Inglês
Published: American Society of Clinical Oncology 2011
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Original Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083873/
https://ncbi.nlm.nih.gov/pubmed/21245435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.29.9024
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