High level of SOX9 in the prostate contributes to increased proliferation and can cooperate with PTEN loss to accelerate neoplasia formation

Developmental pathways have been shown to be important in the initiation and progression of cancer in various tissues. We showed that the transcription factor SOX9 is expressed in the epithelia of the mouse embryonic prostate and is required for proper prostate development. We have performed an in v...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thomsen, Martin K., Ambroisine, Laurence, Wynn, Sarah, Cheah, Kathryn S. E., Foster, Christopher S., Fisher, Gabrielle, Berney, Daniel M., Møller, Henrik, Reuter, Victor E., Scardino, Peter, Cuzick, Jack, Ragavan, Narasimhan, Singh, Paras B., Martin, Francis L., Butler, Christopher M., Cooper, Colin S., Swain, Amanda
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083842/
https://ncbi.nlm.nih.gov/pubmed/20103652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2370
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