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IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells
Nonthyroidal illness syndrome (NTIS) is a state of low serum 3,5,3′ triiodothyronine (T(3)) that occurs in chronically ill patients; the degree of reduction in T(3) is associated with overall prognosis and survival. Iodothyronine deiodinases are enzymes that catalyze iodine removal from thyroid horm...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083773/ https://ncbi.nlm.nih.gov/pubmed/21540553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44678 |
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