Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes

α1-Antitrypsin deficiency is an inherited condition that causes liver disease and emphysema. The normal function of this protein, which is synthesized by the liver, is to inhibit neutrophil elastase, a protease that degrades connective tissue of the lung. In the classical form of the disease, ineffi...

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Detalhes bibliográficos
Main Authors: Ding, Jianqiang, Yannam, Govardhana R., Roy-Chowdhury, Namita, Hidvegi, Tunda, Basma, Hesham, Rennard, Stephen I., Wong, Ronald J., Avsar, Yesim, Guha, Chandan, Perlmutter, David H., Fox, Ira J., Roy-Chowdhury, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083768/
https://ncbi.nlm.nih.gov/pubmed/21505264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45260
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