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JAK2 inhibition prevents innate immune responses and rescues animals from sepsis
Sepsis, a leading cause of death in hospitalized patients, is characterized by lethal systemic inflammatory responses. JAK2 is an essential tyrosine kinase modulating immune responses. However, the implications of JAK2 in infectious disorders remain undetermined. Here, we report that JAK2 inhibitors...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083634/ https://ncbi.nlm.nih.gov/pubmed/20393690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0628-z |
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