Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype

INTRODUCTION: Esmirtazapine is evaluated as a novel drug for treatment of insomnia. PURPOSE: The present study was designed to assess residual effects of single and repeated doses of esmirtazapine 1.5 and 4.5 mg on actual driving in 32 healthy volunteers in a double-blind, placebo-controlled study....

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Библиографические подробности
Главные авторы: Ramaekers, Johannes G., Conen, Silke, de Kam, Pieter Jan, Braat, Sabine, Peeters, Pierre, Theunissen, Eef L., Ivgy-may, Neely
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2011
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083504/
https://ncbi.nlm.nih.gov/pubmed/21246188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2149-4
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