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Therapeutic potential of plasma gelsolin administration in a rat model of sepsis

BACKGROUND: Gelsolin is an actin-binding protein found in the cytoplasm and in extracellular fluids including blood plasma. Plasma gelsolin concentration decreases after a wide range of traumatic injuries. We hypothesized that the repletion of exogenous gelsolin would limit inflammation and tissue i...

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Detalhes bibliográficos
Main Authors: Cohen, Taylor S., Bucki, Robert, Byfield, Fitzroy J., Ciccarelli, Nicholas J., Rosenberg, Brenna, DiNubile, Mark J., Janmey, Paul A., Margulies, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083472/
https://ncbi.nlm.nih.gov/pubmed/21420877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2011.02.006
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