Developmental Enhancement of Adenylate Kinase-AMPK Metabolic Signaling Axis Supports Stem Cell Cardiac Differentiation

BACKGROUND: Energetic and metabolic circuits that orchestrate cell differentiation are largely unknown. Adenylate kinase (AK) and associated AMP-activated protein kinase (AMPK) constitute a major metabolic signaling axis, yet the role of this system in guiding differentiation and lineage specificati...

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Autores principales: Dzeja, Petras P., Chung, Susan, Faustino, Randolph S., Behfar, Atta, Terzic, Andre
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083437/
https://ncbi.nlm.nih.gov/pubmed/21556322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019300
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