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KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia

The histone H3 lysine 36 dimethyl–specific demethylase KDM2b/JHDM1b, which is highly expressed in various human leukemias, was previously found to be important in regulating cell proliferation and cellular senescence. However, its functions in leukemia development and maintenance are unclear. Here,...

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Hlavní autoři: He, Jin, Nguyen, Anh Tram, Zhang, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083299/
https://ncbi.nlm.nih.gov/pubmed/21310926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-312736
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