The Ser(326)Cys Polymorphism of 8-Oxoguanine Glycosylase 1 (OGG1) Is Associated with Type 2 Diabetes in Mexican Americans

OBJECTIVE: Human 8-oxoguanine glycosylase 1 (OGG1) excises oxidatively damaged promutagenic base 8-oxoguanine, a lesion previously observed in a rat model of type 2 diabetes (T2DM). The objective of the present study is to determine whether genetic variation in OGG1 is associated with type 2 diabete...

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Главные авторы: Thameem, Farook, Puppala, Sobha, Lehman, Donna M., Stern, Michael P., Blangero, John, Abboud, Hanna E., Duggirala, Ravindranath, Habib, Samy L.
Формат: Artigo
Язык:Inglês
Опубликовано: S. Karger AG 2010
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083264/
https://ncbi.nlm.nih.gov/pubmed/20606456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000291964
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