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The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors

Carbon monoxide (CO) is produced endogenously by heme oxygenase (HO) enzymes. HO-1 is highly expressed in many inflammatory disease states, where it is broadly protective. The protective effects of HO-1 expression can be largely mimicked by the exogenous application of CO and CO-releasing molecules...

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Detalles Bibliográficos
Main Authors: Wilkinson, William James, Kemp, Paul Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083130/
https://ncbi.nlm.nih.gov/pubmed/21484097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-010-9213-8
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