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Interaction of STAT6 with its co-activator SRC-1/NCoA-1 is regulated by dephosphorylation of the latter via PP2A

Regulation of gene expression represents a central issue in signal-regulated cellular responses. STAT6 is a critical mediator of IL-4 stimulated gene activation. To mediate this function, STAT6 recruits co-activator complexes. We have previously shown that STAT6 binds the PAS-B domain of the co-acti...

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Detalhes bibliográficos
Main Authors: Münz, Tobias, Litterst, Claudia M., Pfitzner, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082895/
https://ncbi.nlm.nih.gov/pubmed/21148148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1225
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