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Enhanced Stimulation of Anti-Ovarian Cancer CD8+ T Cells by Dendritic Cells Loaded with Nanoparticle Encapsulated Tumor Antigen

PROBLEM: Dendritic cell (DC)-based cancer therapies are favored approaches to stimulate anti-tumor T cells responses. Unfortunately, tolerance to tumor antigens is difficult to overcome. Biodegradable poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP) are effective reagents in the delivery of d...

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Detalhes bibliográficos
Main Authors: Hanlon, Douglas J, Aldo, Paulomi B., Devine, Lesley, Alvero, Ayesha B., Engberg, Anna K., Edelson, Richard, Mor, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082607/
https://ncbi.nlm.nih.gov/pubmed/21241402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0897.2010.00968.x
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