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Differentiation Generates Paracrine Cell Pairs That Maintain Basaloid Mouse Mammary Tumors: Proof of Concept

There is a paradox offered up by the cancer stem cell hypothesis. How are the mixed populations that are characteristic of heterogeneous solid tumors maintained at constant proportion, given their high, and different, mitotic indices? In this study, we evaluate a well-characterized mouse model of hu...

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Detalhes bibliográficos
Main Authors: Kim, Soyoung, Goel, Shruti, Alexander, Caroline M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082567/
https://ncbi.nlm.nih.gov/pubmed/21541292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019310
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