hHGF Overexpression in Myoblast Sheets Enhances Their Angiogenic Potential in Rat Chronic Heart Failure

After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling. A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation. We hypothesized that in a rat model of MI-ind...

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Main Authors: Siltanen, Antti, Kitabayashi, Katsukiyo, Lakkisto, Päivi, Mäkelä, Johanna, Pätilä, Tommi, Ono, Masamichi, Tikkanen, Ilkka, Sawa, Yoshiki, Kankuri, Esko, Harjula, Ari
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082550/
https://ncbi.nlm.nih.gov/pubmed/21541335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019161
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