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A Yeast Model of FUS/TLS-Dependent Cytotoxicity
FUS/TLS is a nucleic acid binding protein that, when mutated, can cause a subset of familial amyotrophic lateral sclerosis (fALS). Although FUS/TLS is normally located predominantly in the nucleus, the pathogenic mutant forms of FUS/TLS traffic to, and form inclusions in, the cytoplasm of affected s...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082520/ https://ncbi.nlm.nih.gov/pubmed/21541368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001052 |
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