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ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells
The autosomal recessive hypercholesterolemia protein (ARH) is well known for its role in clathrin-mediated endocytosis of low-density lipoprotein receptors (LDLRs). During uptake, ARH directly binds to the FxNPxY signal in the cytoplasmic tail of LDLR. Interestingly, the same FxNPxY motif is used in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082197/ https://ncbi.nlm.nih.gov/pubmed/21444685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201012121 |
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