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ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells

The autosomal recessive hypercholesterolemia protein (ARH) is well known for its role in clathrin-mediated endocytosis of low-density lipoprotein receptors (LDLRs). During uptake, ARH directly binds to the FxNPxY signal in the cytoplasmic tail of LDLR. Interestingly, the same FxNPxY motif is used in...

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Bibliografski detalji
Glavni autori: Kang, Richard S., Fölsch, Heike
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082197/
https://ncbi.nlm.nih.gov/pubmed/21444685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201012121
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