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Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase
The unfolded protein response (UPR) activates Ire1, an endoplasmic reticulum (ER) resident transmembrane kinase and ribonuclease (RNase), in response to ER stress. We used an in vivo assay, in which disappearance of the UPR-induced spliced HAC1 messenger ribonucleic acid (mRNA) correlates with the r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082189/ https://ncbi.nlm.nih.gov/pubmed/21444691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008071 |
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