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Independent and Joint Modulation of Rat Na(v)1.6 Voltage-Gated Sodium Channels by Coexpression with the Auxiliary β1 and β2 Subunits

The Na(v)1.6 voltage-gated sodium channel α subunit isoform is the most abundant isoform in the brain and is implicated in the transmission of high frequency action potentials. Purification and immunocytochemical studies imply that Na(v)1.6 exist predominantly as Na(v)1.6+β1+β2 heterotrimeric comple...

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Bibliographic Details
Main Authors: Tan, Jianguo, Soderlund, David M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082003/
https://ncbi.nlm.nih.gov/pubmed/21439942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.03.101
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