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A phase I study with an expanded cohort to assess the feasibility of intraperitoneal carboplatin and intravenous paclitaxel in untreated ovarian, fallopian tube, and primary peritoneal carcinoma: A Gynecologic Oncology Group study

PURPOSE: To determine the first-cycle maximum tolerated dose (MTD) of intraperitoneal carboplatin in combination with intravenous paclitaxel and then assess the feasibility of this dose over multiple cycles. METHODS: Beginning at an intraperitoneal (IP) carboplatin dose area under the curve (AUC) of...

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Bibliographische Detailangaben
Hauptverfasser: Morgan, Mark A., Sill, Michael W., Fujiwara, Keiichi, Greer, Benjamin, Rubin, Stephen C., DeGeest, Koen, Yamada, S. Diane, Waggoner, Steven, Coleman, Robert L., Walker, Joan L., Mannel, Robert S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081997/
https://ncbi.nlm.nih.gov/pubmed/21277623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2010.12.358
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