Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

Ischemia-reperfusion (I/R) is a pivotal mechanism of liver damage following liver transplantation or hepatic surgery. We have investigated the effects of cannabidiol(CBD), the non-psychotropic constituent of marijuana, in a mouse model of hepatic I/R injury. I/R triggered time-dependent increases/ch...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, Partha, Rajesh, Mohanraj, Horváth, Béla, Bátkai, Sándor, Park, Ogyi, Tanashian, Galin, Gao, Rachel Y, Patel, Vivek, Wink, David A., Liaudet, Lucas, Haskó, György, Mechoulam, Raphael, Pacher, Pál
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081988/
https://ncbi.nlm.nih.gov/pubmed/21362471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.02.021
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