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Formation of extrachromosomal circular DNA in HeLa cells by nonhomologous recombination.
Extrachromosomal circular DNA (eccDNA) generated from chromosomal DNA is found in all mammalian cells and increases with cell stress or aging. Studies of eccDNA structure and mode of formation provide insight into mechanisms of instability of the mammalian genome. Previous studies have suggested tha...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1994
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC308194/ https://ncbi.nlm.nih.gov/pubmed/8041604 |
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