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Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability
Progesterone withdrawal has been proposed as an underlying factor in premenstrual syndrome and postpartum depression. Progesterone withdrawal induces forced swim test (FST) immobility in mice, a depression-like behavior, but the contribution of specific receptors to this effect is unclear. The role...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081939/ https://ncbi.nlm.nih.gov/pubmed/21163582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2010.11.004 |
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