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Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability

Progesterone withdrawal has been proposed as an underlying factor in premenstrual syndrome and postpartum depression. Progesterone withdrawal induces forced swim test (FST) immobility in mice, a depression-like behavior, but the contribution of specific receptors to this effect is unclear. The role...

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Библиографические подробности
Главные авторы: Beckley, Ethan H., Scibelli, Angela C., Finn, Deborah A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081939/
https://ncbi.nlm.nih.gov/pubmed/21163582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2010.11.004
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