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Dispersal of Group A Streptococcal Biofilms by the Cysteine Protease SpeB Leads to Increased Disease Severity in a Murine Model

Group A Streptococcus (GAS) is a Gram-positive human pathogen best known for causing pharyngeal and mild skin infections. However, in the 1980's there was an increase in severe GAS infections including cellulitis and deeper tissue infections like necrotizing fasciitis. Particularly striking abo...

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Detalhes bibliográficos
Main Authors: Connolly, Kristie L., Roberts, Amity L., Holder, Robert C., Reid, Sean D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081844/
https://ncbi.nlm.nih.gov/pubmed/21547075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018984
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