Evolution from XIST-Independent to XIST-Controlled X-Chromosome Inactivation: Epigenetic Modifications in Distantly Related Mammals

X chromosome inactivation (XCI) is the transcriptional silencing of one X in female mammals, balancing expression of X genes between females (XX) and males (XY). In placental mammals non-coding XIST RNA triggers silencing of one X (Xi) and recruits a characteristic suite of epigenetic modifications,...

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Autores principales: Chaumeil, Julie, Waters, Paul D., Koina, Edda, Gilbert, Clément, Robinson, Terence J., Marshall Graves, Jennifer A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081832/
https://ncbi.nlm.nih.gov/pubmed/21541345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019040
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