Hippocampal responsiveness to 17β-estradiol and equol after long-term ovariectomy: Implication for a therapeutic window of opportunity

A ‘critical window of opportunity’ has been proposed for efficacy of ovarian hormone intervention in peri- and postmenopausal women. We sought to address this hypothesis using a long-term ovariectomized non-human primate (NHP) model, the cynomolgus macaque (Macaca fascicularis). In these studies, we...

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Detalhes bibliográficos
Main Authors: Hamilton, Ryan T., Rettberg, Jamaica R., Mao, Zisu, To, Jimmy, Zhao, Liqin, Appt, Susan E., Register, Thomas C., Kaplan, Jay R., Brinton, Roberta Diaz
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081673/
https://ncbi.nlm.nih.gov/pubmed/21241683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.01.029
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