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NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability

Ionising radiation (IR) is a known carcinogen and poses a significant risk to the haematopoietic system for the development of leukaemia in part by induction of genomic instability. Induction of chronic oxidative stress has been assumed to play an important role in mediating the effect of IR on the...

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Detalhes bibliográficos
Main Authors: Pazhanisamy, Senthil K., Li, Hongliang, Wang, Yong, Batinic-Haberle, Ines, Zhou, Daohong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081334/
https://ncbi.nlm.nih.gov/pubmed/21415439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ger001
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