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LOXL1 Promoter Haplotypes Are Associated with Exfoliation Syndrome in a U.S. Caucasian Population

PURPOSE. LOXL1 is a major genetic risk factor for exfoliation syndrome (ES) and exfoliation glaucoma (EG). Recent evidence documenting reversal of risk alleles for the disease-associated missense variants R141L and G153D suggests that these variants are not causative and that they may be proxies for...

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Detalhes bibliográficos
Main Authors: Fan, Bao Jian, Pasquale, Louis R., Rhee, Douglas, Li, Tiansen, Haines, Jonathan L., Wiggs, Janey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081229/
https://ncbi.nlm.nih.gov/pubmed/21212179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6268
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