N-Acetylcysteine Amide (NACA) Prevents Retinal Degeneration by Up-Regulating Reduced Glutathione Production and Reversing Lipid Peroxidation

Oxidative stress plays a critical role in accelerating retinal pigment epithelial dysfunction and death in degenerative retinal diseases, including age-related macular degeneration. Given the key role of oxidative stress–induced retinal pigment epithelial cell death and secondary photoreceptor loss...

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Autors principals: Schimel, Andrew M., Abraham, Linu, Cox, Douglas, Sene, Abdoulaye, Kraus, Courtney, Dace, Dru S., Ercal, Nuran, Apte, Rajendra S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081196/
https://ncbi.nlm.nih.gov/pubmed/21457933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.036
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