Aberrant Cell Proliferation by Enhanced Mitochondrial Biogenesis via mtTFA in Arsenical Skin Cancers

Arsenic-induced Bowen's disease (As-BD), a cutaneous carcinoma in situ, is thought to arise from gene mutation and uncontrolled proliferation. However, how mitochondria regulate the arsenic-induced cell proliferation remains unclear. The aim of this study was to clarify whether arsenic interfer...

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Detalhes bibliográficos
Main Authors: Lee, Chih-Hung, Wu, Shi-Bei, Hong, Chien-Hui, Liao, Wei-Ting, Wu, Ching-Ying, Chen, Gwo-Shing, Wei, Yau-Huei, Yu, Hsin-Su
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081159/
https://ncbi.nlm.nih.gov/pubmed/21514422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.056
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