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Mitochondrial optic neuropathies – Disease mechanisms and therapeutic strategies
Leber hereditary optic neuropathy (LHON) and autosomal-dominant optic atrophy (DOA) are the two most common inherited optic neuropathies in the general population. Both disorders share striking pathological similarities, marked by the selective loss of retinal ganglion cells (RGCs) and the early inv...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Pergamon
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081075/ https://ncbi.nlm.nih.gov/pubmed/21112411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preteyeres.2010.11.002 |
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