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Effect of abasic linker substitution on triplex formation, Sp1 binding, and specificity in an oligonucleotide targeted to the human Ha-ras promoter.

A region of the human Ha-ras promoter (-8 to -28) which contains two of the three Sp1 binding sites essential for transcriptional activity forms a sequence specific oligonucleotide-directed pur*pur:pyr triple helix. The relative binding of oligonucleotides containing different substitutions, includi...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Mayfield, C, Miller, D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1994
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308093/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8208618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.10.1909
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