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Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector.

Mutagenesis at abasic sites was investigated in E.coli and simian kidney (COS) cells using a duplex shuttle vector containing synthetic analogs of deoxyribose on the phosphodiester backbone. Lesions were positioned on opposite strands of the vector. When the tetrahydrofuranyl analog was used as the...

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Bibliografiske detaljer
Main Authors: Takeshita, M, Eisenberg, W
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC308091/
https://ncbi.nlm.nih.gov/pubmed/8208616
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