Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response

We recently demonstrated that the respiratory syncytial virus (RSV) NS1 protein, an antagonist of host type I interferon (IFN-I) production and signaling, has a suppressive effect on the maturation of human dendritic cells (DC) that was only partly dependent on released IFN-I. Here we investigated w...

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Main Authors: Munir, Shirin, Hillyer, Philippa, Le Nouën, Cyril, Buchholz, Ursula J., Rabin, Ronald L., Collins, Peter L., Bukreyev, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080852/
https://ncbi.nlm.nih.gov/pubmed/21533073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001336
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