A Rapid Generalized Least Squares Model for a Genome-Wide Quantitative Trait Association Analysis in Families

Genome-wide association studies (GWAS) using family data involve association analyses between hundreds of thousands of markers and a trait for a large number of related individuals. The correlations among relatives bring statistical and computational challenges when performing these large-scale asso...

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Autores principales: Li, Xiang, Basu, Saonli, Miller, Michael B., Iacono, William G., McGue, Matt
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2011
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080778/
https://ncbi.nlm.nih.gov/pubmed/21474944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324839
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