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Association of beta-adrenergic receptor polymorphisms and mortality in carvedilol-treated chronic heart-failure patients

AIM: Pharmacogenetics can be used as a tool for stratified pharmacological therapy in cardiovascular medicine. We investigated whether a predefined combination of the Arg389Gly polymorphism in the adrenergic β(1)-receptor gene (ADRB1) and the Gln27Glu polymorphism in the adrenergic β(2)-receptor gen...

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Main Authors: Petersen, Morten, Andersen, Jon T, Hjelvang, Brian R, Broedbaek, Kasper, Afzal, Shoaib, Nyegaard, Mette, Børglum, Anders D, Stender, Steen, Køber, Lars, Torp-Pedersen, Christian, Poulsen, Henrik E
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080644/
https://ncbi.nlm.nih.gov/pubmed/21395649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03868.x
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