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Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

AIMS: A hydrofluoroalkane formulation of budesonide pressurized metered-dose inhaler has been developed to replace the existing chlorofluorocarbon one. The aim of this study was to evaluate the pharmacokinetic and pharmacodynamic characteristics of both formulations. METHODS: Systemic bioavailabilit...

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Detalhes bibliográficos
Main Authors: Clearie, Karine L, Williamson, Peter A, Meldrum, Karen, Gillen, Michael, Carlsson, Lars-Goran, Carlholm, Marie, Ekelund, Jan, Lipworth, Brian J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080637/
https://ncbi.nlm.nih.gov/pubmed/21395643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03857.x
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