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Yeast DEL Assay Detects Protection against Radiation-Induced Cytotoxicity and Genotoxicity: Adaptation of a Microtiter Plate Version

The DEL assay in yeast detects DNA deletions that are inducible by many carcinogens. Here we use the colorimetric agent MTS to adapt the yeast DEL assay for microwell plate measurement of ionizing radiation-induced cell killing and DNA deletions. Using the microwell-based DEL assay, cell killing and...

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Main Authors: Hafer, Kurt, Rivina, Yelena, Schiestl, Robert H.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080456/
https://ncbi.nlm.nih.gov/pubmed/21128795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2059.1
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