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Fyn is Induced by Ras/PI3K/Akt Signaling and is Required for Enhanced Invasion/Migration

Src family kinases (SFKs) are frequently over-expressed and/or activated in human cancers, and play key roles in cancer cell invasion, metastasis, proliferation, survival and angiogenesis. Allosteric activation of SFKs occurs through well-defined post-translational mechanisms, however the SFK member...

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Detalhes bibliográficos
Main Authors: Yadav, Vipin, Denning, Mitchell F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080437/
https://ncbi.nlm.nih.gov/pubmed/21480388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20716
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