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Probing the hammerhead ribozyme structure with ribonucleases.

Susceptibility to RNase digestion has been used to probe the conformation of the hammerhead ribozyme structure prepared from chemically synthesised RNAs. Less than about 1.5% of the total sample was digested to obtain a profile of RNase digestion sites. The observed digestion profiles confirmed the...

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Hodgson, R A, Shirley, N J, Symons, R H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1994
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.9.1620
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