Ubiquitin-Dependent Control of Class II MHC Localization Is Dispensable for Antigen Presentation and Antibody Production

Controlled localization of class II MHC molecules is essential for proper class II MHC-restricted antigen presentation and the subsequent initiation of an adaptive immune response. Ubiquitination of class II MHC molecules on cytosolic lysine (K225) of the β-chain has been shown to affect localizatio...

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Main Authors: McGehee, Annette M., Strijbis, Karin, Guillen, Eduardo, Eng, Thomas, Kirak, Oktay, Ploegh, Hidde L.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080378/
https://ncbi.nlm.nih.gov/pubmed/21533087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018817
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