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Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif.

In the recently discovered i-motif, four stretches of cytosine form two parallel-stranded duplexes whose C.C+ base pairs are fully intercalated. The i-motif may be recognized by characteristic Overhauser cross-peaks of the proton NMR spectrum, reflecting short H1'-H1' distances across the...

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Bibliographic Details
Main Authors: Leroy, J L, Guéron, M, Mergny, J L, Hélène, C
Format: Artigo
Language:Inglês
Published: 1994
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC308035/
https://ncbi.nlm.nih.gov/pubmed/8202359
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