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Proximity ligation in situ assay for monitoring the global DNA methylation in cells
BACKGROUND: DNA methylation has a central role in the epigenetic control of mammalian gene expression, and is required for X inactivation, genomics imprinting and silencing of retrotransposons and repetitive sequences. Thus, several technologies have been developed to measure the degree of DNA methy...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080290/ https://ncbi.nlm.nih.gov/pubmed/21470401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-31 |
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