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Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous system

The specific functions of intrinsic regulators of oligodendrocyte progenitor cell (OPC) division are poorly understood. Type 2 cyclin-dependent kinase (Cdk2) controls cell cycle progression of OPCs, but whether it acts during myelination and repair of demyelinating lesions remains unexplored. Here,...

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Détails bibliographiques
Auteurs principaux: Caillava, Céline, Vandenbosch, Renaud, Jablonska, Beata, Deboux, Cyrille, Spigoni, Giulia, Gallo, Vittorio, Malgrange, Brigitte, Baron-Van Evercooren, Anne
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080270/
https://ncbi.nlm.nih.gov/pubmed/21502361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004146
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